Monday, March 26, 2007

UF experts urge caution with diet pill called Alli

University of Florida health experts caution students about a former prescription diet pill that blocks the absorption of fat.

The pill recently approved by the Food and Drug Administration for sale over the counter is a reduced-strength version of Orlistat and will be sold as Alli.

Anne Kendall, a lecturer in the Food Science and Human Nutrition Department, said the pill blocks the absorption of fat consumed and the fat is then transferred to the stool.

Kendall said the pill is not a "magic bullet."

According to the Alli Web site, for every 5 pounds lost from dieting, Alli can take off an additional 2 to 3 pounds.

Kendall said the pill can cause diarrhea and deficiencies in vitamins A, D, E and K, but a multivitamin can help.

Kendall explained that Alli was probably approved because the research didn't present dangerous side effects since it's a lower dose. "One of the key things is to use it as directed," she said. "There's no guarantee that people won't take larger doses than recommended."

A larger intake of the pill could leave the organs unprotected because more fat is being blocked, she said.

Alli alone won't block all the fat absorption, which is why diet and exercise is required, she said.

Mark Murphy, a personal trainer intern at the Department of Recreational Sports, said he would warn anyone he was training against using artificial products. He said he thinks anyone using a weight-loss pill is avoiding a workout.

Murphy said he dealt with a female student who used a diet pill and lost 7 pounds in two weeks to prepare for Spring Break. During the break the student regained the weight because she had only shed water weight. He explained she became sick because of dehydration and alcohol.

He said just because a person looks good on the outside, it doesn't mean they're healthy inside. He said it's important to monitor heart rate, blood pressure and bowel movements, if using a diet pill.

Mariana Fonseca, 19, a dietetics major, said she doesn't know if Alli will become popular on campus, but she does not support the use of diet pills.

Exercise and diet alone are the healthiest ways to lose weight, even for those who are obese, she said. "People are going to think this is a miracle pill and that's bad because it's not," she said. "It's healthy to lose 1 or 2 pounds a week."

Fonseca counts calories and exercises as part of a regimen for a health condition that can cause her to gain weight. "Whatever you put into your body is what you get out of it," she said.

Diet Pill alli Begins Recruiting 400 Would-Be Dieters for Prelaunch Test

Diet pill alli (low-dose Xenical) has begun recruiting 400 would-be dieters for a prelaunch test of educational program being designed to support the first FDA-approved over-the-counter diet drug.

Several readers of our sister site, alliReport.com, report they have received emails inviting them to apply to become part of something called the alli First Team Community, which is built around a password-protected online forum.

"As a member of the alli First Team community, you will be provided with the only FDA-approved weight loss product (alli capsules), educational materials and tools to help you on your journey, and an on-line community to support your efforts," the email said.

"If you are selected to join this community, we ask that you read the materials that we’ll send you to help you get ready, take alli with each meal containing fat, keep a daily food journal, log in to the community and contribute your thoughts (via surveys, bulletin boards, chats, etc.) at least once a week.

"You can expect to spend 10-15 minutes online per week. In addition to sharing tips and building friendships with other members, you will receive a free supply of alli for 6 months," the email added.

GlaxoSmithKline said it would send participants the first 3-month supply of the diet pill prior to its being available in stores, suggesting -- since next week is April -- that alli will not be generally available until at least July.

The email also indicated that participants in the trial who follow the alli program and are successfully losing weight may also be asked to become part of the alli public relations program and speak to members of the media about their experiences.

If you are selected for the alli First Team community, please keep the alliReport.com posted on your experiences.